Muscleblind-like protein 1 (MBNL1)
Homo sapiens — UniProt Q9NR56
Data last refreshed: (UniProt release unknown)
Key facts
Muscleblind-like protein 1 (MBNL1) is a protein from Homo sapiens identified by UniProt accession Q9NR56, 388 residues long. MolForge cross-references it against 0 known binders and 256 disease associations.
- UniProt accession: Q9NR56; gene symbol MBNL1.
- Organism: Homo sapiens.
- Length: 388 amino acids.
- Top disease associations (Open Targets): neutrophil count, testosterone measurement and type 2 diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Muscleblind-like protein 1 |
|---|---|
| UniProt accession | Q9NR56 |
| Gene | MBNL1 |
| Organism | Homo sapiens |
| Length | 388 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (256)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.41
- testosterone measurement · score 0.40
- type 2 diabetes mellitus · score 0.39
- body height · score 0.38
- leukocyte count · score 0.38
- Fuchs endothelial corneal dystrophy · score 0.37
- aspartate aminotransferase measurement · score 0.37
- corneal dystrophy, Fuchs endothelial, 3 · score 0.37
- serum alanine aminotransferase measurement · score 0.36
- lymphocyte count · score 0.36
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NR56-F1 | alphafold | PREDICTED | 66.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NR56.
Amino-acid sequence (388 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MBNL1?
The strongest Open Targets associations for MBNL1 are neutrophil count, testosterone measurement, type 2 diabetes mellitus, body height and leukocyte count.
How long is the MBNL1 protein?
The Homo sapiens MBNL1 protein (UniProt Q9NR56) is 388 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NR56 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NR56 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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