Platelet-derived growth factor C (PDGFC)
Homo sapiens — UniProt Q9NRA1
Data last refreshed: (UniProt release unknown)
Key facts
Platelet-derived growth factor C (PDGFC) is a protein from Homo sapiens identified by UniProt accession Q9NRA1, 345 residues long. MolForge cross-references it against 0 known binders and 347 disease associations.
- UniProt accession: Q9NRA1; gene symbol PDGFC.
- Organism: Homo sapiens.
- Length: 345 amino acids.
- Top disease associations (Open Targets): systolic blood pressure, platelet count and triglyceride measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Platelet-derived growth factor C |
|---|---|
| UniProt accession | Q9NRA1 |
| Gene | PDGFC |
| Organism | Homo sapiens |
| Length | 345 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (347)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.49
- platelet count · score 0.48
- triglyceride measurement · score 0.47
- high density lipoprotein cholesterol measurement · score 0.46
- hematocrit · score 0.46
- reticulocyte count · score 0.45
- reticulocyte measurement · score 0.42
- sex hormone-binding globulin measurement · score 0.42
- type 2 diabetes mellitus · score 0.42
- diastolic blood pressure · score 0.42
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRA1-F1 | alphafold | PREDICTED | 75.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRA1.
Amino-acid sequence (345 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PDGFC?
The strongest Open Targets associations for PDGFC are systolic blood pressure, platelet count, triglyceride measurement, high density lipoprotein cholesterol measurement and hematocrit.
How long is the PDGFC protein?
The Homo sapiens PDGFC protein (UniProt Q9NRA1) is 345 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRA1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRA1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.