Eukaryotic translation initiation factor 4E transporter (EIF4ENIF1)
Homo sapiens — UniProt Q9NRA8
Data last refreshed: (UniProt release unknown)
Key facts
Eukaryotic translation initiation factor 4E transporter (EIF4ENIF1) is a protein from Homo sapiens identified by UniProt accession Q9NRA8, 985 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q9NRA8; gene symbol EIF4ENIF1.
- Organism: Homo sapiens.
- Length: 985 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): neurodegenerative disease, lysosomal storage disease and primary ovarian insufficiency.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Eukaryotic translation initiation factor 4E transporter |
|---|---|
| UniProt accession | Q9NRA8 |
| Gene | EIF4ENIF1 |
| Organism | Homo sapiens |
| Length | 985 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- lysosomal storage disease · score 0.35
- primary ovarian insufficiency · score 0.23
- Premature ovarian insufficiency · score 0.18
- premature menopause · score 0.18
- BMI-adjusted waist circumference · score 0.09
- diet measurement · score 0.09
- neutrophil percentage of leukocytes · score 0.07
- leukocyte count · score 0.07
- cortical surface area measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRA8-F1 | alphafold | PREDICTED | 50.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRA8.
Amino-acid sequence (985 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EIF4ENIF1?
The strongest Open Targets associations for EIF4ENIF1 are neurodegenerative disease, lysosomal storage disease, primary ovarian insufficiency, Premature ovarian insufficiency and premature menopause.
How long is the EIF4ENIF1 protein?
The Homo sapiens EIF4ENIF1 protein (UniProt Q9NRA8) is 985 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRA8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRA8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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