Carbohydrate sulfotransferase 12 (CHST12)
Homo sapiens — UniProt Q9NRB3
Data last refreshed: (UniProt release unknown)
Key facts
Carbohydrate sulfotransferase 12 (CHST12) is a protein from Homo sapiens identified by UniProt accession Q9NRB3, 414 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.
- UniProt accession: Q9NRB3; gene symbol CHST12.
- Organism: Homo sapiens.
- Length: 414 amino acids.
- Top disease associations (Open Targets): blood protein measurement, neutrophil count and multiple sclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Carbohydrate sulfotransferase 12 |
|---|---|
| UniProt accession | Q9NRB3 |
| Gene | CHST12 |
| Organism | Homo sapiens |
| Length | 414 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (95)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.35
- neutrophil count · score 0.27
- multiple sclerosis · score 0.26
- pappalysin‐1 measurement · score 0.25
- serum albumin measurement · score 0.15
- platelet count · score 0.13
- monocyte percentage of leukocytes · score 0.11
- diastolic blood pressure · score 0.09
- reticulocyte count · score 0.08
- glioblastoma multiforme · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRB3-F1 | alphafold | PREDICTED | 83.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRB3.
Amino-acid sequence (414 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHST12?
The strongest Open Targets associations for CHST12 are blood protein measurement, neutrophil count, multiple sclerosis, pappalysin‐1 measurement and serum albumin measurement.
How long is the CHST12 protein?
The Homo sapiens CHST12 protein (UniProt Q9NRB3) is 414 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRB3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRB3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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