Otoraplin (OTOR)
Homo sapiens — UniProt Q9NRC9
Data last refreshed: (UniProt release unknown)
Key facts
Otoraplin (OTOR) is a protein from Homo sapiens identified by UniProt accession Q9NRC9, 128 residues long. MolForge cross-references it against 0 known binders and 192 disease associations.
- UniProt accession: Q9NRC9; gene symbol OTOR.
- Organism: Homo sapiens.
- Length: 128 amino acids.
- Top disease associations (Open Targets): mean platelet volume, monocyte count and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Otoraplin |
|---|---|
| UniProt accession | Q9NRC9 |
| Gene | OTOR |
| Organism | Homo sapiens |
| Length | 128 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (192)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.33
- monocyte count · score 0.33
- mean corpuscular hemoglobin · score 0.32
- mean corpuscular volume · score 0.32
- platelet count · score 0.32
- leukocyte count · score 0.32
- hemoglobin measurement · score 0.32
- erythrocyte count · score 0.32
- hematocrit · score 0.32
- mean corpuscular hemoglobin concentration · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRC9-F1 | alphafold | PREDICTED | 88.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRC9.
Amino-acid sequence (128 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OTOR?
The strongest Open Targets associations for OTOR are mean platelet volume, monocyte count, mean corpuscular hemoglobin, mean corpuscular volume and platelet count.
How long is the OTOR protein?
The Homo sapiens OTOR protein (UniProt Q9NRC9) is 128 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRC9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRC9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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