F-box only protein 6 (FBXO6)
Homo sapiens — UniProt Q9NRD1
Data last refreshed: (UniProt release unknown)
Key facts
F-box only protein 6 (FBXO6) is a protein from Homo sapiens identified by UniProt accession Q9NRD1, 293 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q9NRD1; gene symbol FBXO6.
- Organism: Homo sapiens.
- Length: 293 amino acids.
- Top disease associations (Open Targets): gastric adenocarcinoma, ovarian cancer and endometrial cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box only protein 6 |
|---|---|
| UniProt accession | Q9NRD1 |
| Gene | FBXO6 |
| Organism | Homo sapiens |
| Length | 293 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- gastric adenocarcinoma · score 0.25
- ovarian cancer · score 0.25
- endometrial cancer · score 0.25
- breast adenocarcinoma · score 0.25
- blood protein measurement · score 0.18
- periodontal disorder · score 0.09
- nail-patella syndrome · score 0.07
- microphthalmia with limb anomalies · score 0.07
- basophil percentage of leukocytes · score 0.05
- basophil count · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRD1-F1 | alphafold | PREDICTED | 88.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRD1.
Amino-acid sequence (293 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FBXO6?
The strongest Open Targets associations for FBXO6 are gastric adenocarcinoma, ovarian cancer, endometrial cancer, breast adenocarcinoma and blood protein measurement.
How long is the FBXO6 protein?
The Homo sapiens FBXO6 protein (UniProt Q9NRD1) is 293 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRD1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRD1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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