Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1)
Homo sapiens — UniProt Q9NRG1
Data last refreshed: (UniProt release unknown)
Key facts
Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1) is a protein from Homo sapiens identified by UniProt accession Q9NRG1, 225 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q9NRG1; gene symbol PRTFDC1.
- Organism: Homo sapiens.
- Length: 225 amino acids.
- Top disease associations (Open Targets): reticulocyte count, monocyte count and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Phosphoribosyltransferase domain-containing protein 1 |
|---|---|
| UniProt accession | Q9NRG1 |
| Gene | PRTFDC1 |
| Organism | Homo sapiens |
| Length | 225 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.52
- monocyte count · score 0.51
- lymphocyte count · score 0.50
- platelet count · score 0.50
- neutrophil count · score 0.50
- lean body mass · score 0.50
- eosinophil count · score 0.50
- Red cell distribution width · score 0.49
- leukocyte count · score 0.48
- body height · score 0.46
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRG1-F1 | alphafold | PREDICTED | 90.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRG1.
Amino-acid sequence (225 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRTFDC1?
The strongest Open Targets associations for PRTFDC1 are reticulocyte count, monocyte count, lymphocyte count, platelet count and neutrophil count.
How long is the PRTFDC1 protein?
The Homo sapiens PRTFDC1 protein (UniProt Q9NRG1) is 225 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRG1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRG1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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