Aladin (AAAS)
Homo sapiens — UniProt Q9NRG9
Data last refreshed: (UniProt release unknown)
Key facts
Aladin (AAAS) is a protein from Homo sapiens identified by UniProt accession Q9NRG9, 546 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q9NRG9; gene symbol AAAS.
- Organism: Homo sapiens.
- Length: 546 amino acids.
- Top disease associations (Open Targets): triple-A syndrome, Triple A syndrome and HIV infection.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Aladin |
|---|---|
| UniProt accession | Q9NRG9 |
| Gene | AAAS |
| Organism | Homo sapiens |
| Length | 546 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- triple-A syndrome · score 0.77
- Triple A syndrome · score 0.73
- HIV infection · score 0.54
- influenza · score 0.54
- viral disease · score 0.53
- genetic disorder · score 0.45
- achalasia-alacrima syndrome · score 0.42
- Histiocytosis · score 0.37
- COVID-19 · score 0.37
- Hyperreflexia · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRG9-F1 | alphafold | PREDICTED | 75.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRG9.
Amino-acid sequence (546 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AAAS?
The strongest Open Targets associations for AAAS are triple-A syndrome, Triple A syndrome, HIV infection, influenza and viral disease.
How long is the AAAS protein?
The Homo sapiens AAAS protein (UniProt Q9NRG9) is 546 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRG9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRG9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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