Protein YAE1 homolog (YAE1)
Homo sapiens — UniProt Q9NRH1
Data last refreshed: (UniProt release unknown)
Key facts
Protein YAE1 homolog (YAE1) is a protein from Homo sapiens identified by UniProt accession Q9NRH1, 226 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q9NRH1; gene symbol YAE1.
- Organism: Homo sapiens.
- Length: 226 amino acids.
- Top disease associations (Open Targets): attention deficit hyperactivity disorder, mean corpuscular hemoglobin concentration and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein YAE1 homolog |
|---|---|
| UniProt accession | Q9NRH1 |
| Gene | YAE1 |
| Organism | Homo sapiens |
| Length | 226 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- attention deficit hyperactivity disorder · score 0.25
- mean corpuscular hemoglobin concentration · score 0.25
- mean corpuscular hemoglobin · score 0.24
- monocyte percentage of leukocytes · score 0.23
- body mass index · score 0.08
- grip strength measurement · score 0.08
- opioid use disorder · score 0.07
- vital capacity · score 0.07
- body fat percentage · score 0.07
- self reported educational attainment · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRH1-F1 | alphafold | PREDICTED | 70.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRH1.
Amino-acid sequence (226 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with YAE1?
The strongest Open Targets associations for YAE1 are attention deficit hyperactivity disorder, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, monocyte percentage of leukocytes and body mass index.
How long is the YAE1 protein?
The Homo sapiens YAE1 protein (UniProt Q9NRH1) is 226 amino acids long.
Browse: Targets: Y · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRH1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRH1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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