SNF-related serine/threonine-protein kinase (SNRK)
Homo sapiens — UniProt Q9NRH2
Data last refreshed: (UniProt release unknown)
Key facts
SNF-related serine/threonine-protein kinase (SNRK) is a protein from Homo sapiens identified by UniProt accession Q9NRH2, 765 residues long. MolForge cross-references it against 2 known binders and 68 disease associations.
- UniProt accession: Q9NRH2; gene symbol SNRK.
- Organism: Homo sapiens.
- Length: 765 amino acids.
- Target class: Kinase.
- Top disease associations (Open Targets): neurodegenerative disease, lysosomal storage disease and Alzheimer disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SNF-related serine/threonine-protein kinase |
|---|---|
| UniProt accession | Q9NRH2 |
| Gene | SNRK |
| Organism | Homo sapiens |
| Length | 765 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Kinase (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (68)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.55
- lysosomal storage disease · score 0.47
- Alzheimer disease · score 0.42
- Parkinson disease · score 0.42
- multiple sclerosis · score 0.42
- emotional symptom measurement · score 0.23
- gastroesophageal reflux disease · score 0.19
- attention deficit hyperactivity disorder · score 0.19
- antisocial behaviour measurement · score 0.19
- substance abuse · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRH2-F1 | alphafold | PREDICTED | 57.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRH2.
Amino-acid sequence (765 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNRK?
The strongest Open Targets associations for SNRK are neurodegenerative disease, lysosomal storage disease, Alzheimer disease, Parkinson disease and multiple sclerosis.
How long is the SNRK protein?
The Homo sapiens SNRK protein (UniProt Q9NRH2) is 765 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRH2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRH2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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