Tubulin gamma-2 chain (TUBG2)
Homo sapiens — UniProt Q9NRH3
Data last refreshed: (UniProt release unknown)
Key facts
Tubulin gamma-2 chain (TUBG2) is a protein from Homo sapiens identified by UniProt accession Q9NRH3, 451 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.
- UniProt accession: Q9NRH3; gene symbol TUBG2.
- Organism: Homo sapiens.
- Length: 451 amino acids.
- Top disease associations (Open Targets): type 2 diabetes mellitus, whole body water mass and body weight.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tubulin gamma-2 chain |
|---|---|
| UniProt accession | Q9NRH3 |
| Gene | TUBG2 |
| Organism | Homo sapiens |
| Length | 451 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (57)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.13
- whole body water mass · score 0.13
- body weight · score 0.11
- vitamin D measurement · score 0.10
- psoriasis · score 0.10
- appendicular lean mass · score 0.09
- Drugs used in diabetes use measurement · score 0.08
- cortical surface area measurement · score 0.07
- hemoglobin A1 measurement · score 0.07
- lymphocyte count · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRH3-F1 | alphafold | PREDICTED | 91.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRH3.
Amino-acid sequence (451 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TUBG2?
The strongest Open Targets associations for TUBG2 are type 2 diabetes mellitus, whole body water mass, body weight, vitamin D measurement and psoriasis.
How long is the TUBG2 protein?
The Homo sapiens TUBG2 protein (UniProt Q9NRH3) is 451 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRH3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRH3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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