C-C motif chemokine 28 (CCL28)
Homo sapiens — UniProt Q9NRJ3
Data last refreshed: (UniProt release unknown)
Key facts
C-C motif chemokine 28 (CCL28) is a protein from Homo sapiens identified by UniProt accession Q9NRJ3, 127 residues long. MolForge cross-references it against 0 known binders and 164 disease associations.
- UniProt accession: Q9NRJ3; gene symbol CCL28.
- Organism: Homo sapiens.
- Length: 127 amino acids.
- Top disease associations (Open Targets): ovarian cancer, breast adenocarcinoma and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-C motif chemokine 28 |
|---|---|
| UniProt accession | Q9NRJ3 |
| Gene | CCL28 |
| Organism | Homo sapiens |
| Length | 127 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (164)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.26
- breast adenocarcinoma · score 0.17
- head and neck squamous cell carcinoma · score 0.16
- lymphocyte count · score 0.16
- mean platelet volume · score 0.15
- Red cell distribution width · score 0.11
- neoplasm · score 0.10
- prostate adenocarcinoma · score 0.10
- reticulocyte count · score 0.09
- breast cancer · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRJ3-F1 | alphafold | PREDICTED | 72.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRJ3.
Amino-acid sequence (127 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCL28?
The strongest Open Targets associations for CCL28 are ovarian cancer, breast adenocarcinoma, head and neck squamous cell carcinoma, lymphocyte count and mean platelet volume.
How long is the CCL28 protein?
The Homo sapiens CCL28 protein (UniProt Q9NRJ3) is 127 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRJ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRJ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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