Tubby-related protein 4 (TULP4)
Homo sapiens — UniProt Q9NRJ4
Data last refreshed: (UniProt release unknown)
Key facts
Tubby-related protein 4 (TULP4) is a protein from Homo sapiens identified by UniProt accession Q9NRJ4, 1543 residues long. MolForge cross-references it against 0 known binders and 115 disease associations.
- UniProt accession: Q9NRJ4; gene symbol TULP4.
- Organism: Homo sapiens.
- Length: 1543 amino acids.
- Top disease associations (Open Targets): body height, vital capacity and neutrophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tubby-related protein 4 |
|---|---|
| UniProt accession | Q9NRJ4 |
| Gene | TULP4 |
| Organism | Homo sapiens |
| Length | 1543 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (115)
Diseases linked to this target (Open Targets).
- body height · score 0.50
- vital capacity · score 0.45
- neutrophil count · score 0.45
- forced expiratory volume · score 0.42
- appendicular lean mass · score 0.42
- platelet crit · score 0.39
- heel bone mineral density · score 0.37
- neurodegenerative disease · score 0.37
- lipoprotein A measurement · score 0.34
- fat body mass · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRJ4-F1 | alphafold | PREDICTED | 53.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRJ4.
Amino-acid sequence (1543 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TULP4?
The strongest Open Targets associations for TULP4 are body height, vital capacity, neutrophil count, forced expiratory volume and appendicular lean mass.
How long is the TULP4 protein?
The Homo sapiens TULP4 protein (UniProt Q9NRJ4) is 1543 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRJ4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRJ4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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