Protocadherin beta-16 (PCDHB16)
Homo sapiens — UniProt Q9NRJ7
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin beta-16 (PCDHB16) is a protein from Homo sapiens identified by UniProt accession Q9NRJ7, 776 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9NRJ7; gene symbol PCDHB16.
- Organism: Homo sapiens.
- Length: 776 amino acids.
- Top disease associations (Open Targets): body height, medulloblastoma and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin beta-16 |
|---|---|
| UniProt accession | Q9NRJ7 |
| Gene | PCDHB16 |
| Organism | Homo sapiens |
| Length | 776 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- body height · score 0.05
- medulloblastoma · score 0.02
- glioblastoma multiforme · score 0.01
- clear cell renal carcinoma · score 0.01
- diabetes mellitus · score 0.01
- oligodendroglioma · score 0.01
- psoriasis · score 0.01
- cancer · score 0.01
- ovarian carcinoma · score 0.01
- astrocytoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRJ7-F1 | alphafold | PREDICTED | 82.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRJ7.
Amino-acid sequence (776 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHB16?
The strongest Open Targets associations for PCDHB16 are body height, medulloblastoma, glioblastoma multiforme, clear cell renal carcinoma and diabetes mellitus.
How long is the PCDHB16 protein?
The Homo sapiens PCDHB16 protein (UniProt Q9NRJ7) is 776 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRJ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRJ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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