ATP-binding cassette sub-family B member 10, mitochondrial (ABCB10)
Homo sapiens — UniProt Q9NRK6
Data last refreshed: (UniProt release unknown)
Key facts
ATP-binding cassette sub-family B member 10, mitochondrial (ABCB10) is a protein from Homo sapiens identified by UniProt accession Q9NRK6, 738 residues long. MolForge cross-references it against 0 known binders and 130 disease associations.
- UniProt accession: Q9NRK6; gene symbol ABCB10.
- Organism: Homo sapiens.
- Length: 738 amino acids.
- Top disease associations (Open Targets): type 2 diabetes mellitus, mean corpuscular hemoglobin and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ATP-binding cassette sub-family B member 10, mitochondrial |
|---|---|
| UniProt accession | Q9NRK6 |
| Gene | ABCB10 |
| Organism | Homo sapiens |
| Length | 738 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (130)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.39
- mean corpuscular hemoglobin · score 0.37
- neurodegenerative disease · score 0.37
- HbA1c measurement · score 0.31
- eosinophil count · score 0.30
- hemoglobin A1 measurement · score 0.26
- glucose measurement · score 0.26
- eosinophil percentage of leukocytes · score 0.20
- Drugs used in diabetes use measurement · score 0.18
- blood protein measurement · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRK6-F1 | alphafold | PREDICTED | 80.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRK6.
Amino-acid sequence (738 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ABCB10?
The strongest Open Targets associations for ABCB10 are type 2 diabetes mellitus, mean corpuscular hemoglobin, neurodegenerative disease, HbA1c measurement and eosinophil count.
How long is the ABCB10 protein?
The Homo sapiens ABCB10 protein (UniProt Q9NRK6) is 738 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRK6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRK6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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