Interleukin-17 receptor B (IL17RB)
Homo sapiens — UniProt Q9NRM6
Data last refreshed: (UniProt release unknown)
Key facts
Interleukin-17 receptor B (IL17RB) is a protein from Homo sapiens identified by UniProt accession Q9NRM6, 502 residues long. MolForge cross-references it against 0 known binders and 286 disease associations.
- UniProt accession: Q9NRM6; gene symbol IL17RB.
- Organism: Homo sapiens.
- Length: 502 amino acids.
- Top disease associations (Open Targets): interleukin 17 receptor B measurement, cardiovascular disease and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Interleukin-17 receptor B |
|---|---|
| UniProt accession | Q9NRM6 |
| Gene | IL17RB |
| Organism | Homo sapiens |
| Length | 502 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (286)
Diseases linked to this target (Open Targets).
- interleukin 17 receptor B measurement · score 0.25
- cardiovascular disease · score 0.15
- body mass index · score 0.12
- Abnormality of refraction · score 0.11
- hypertension · score 0.11
- testosterone measurement · score 0.11
- diastolic blood pressure · score 0.10
- systolic blood pressure · score 0.10
- refractive error · score 0.10
- self reported educational attainment · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRM6-F1 | alphafold | PREDICTED | 79.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRM6.
Amino-acid sequence (502 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IL17RB?
The strongest Open Targets associations for IL17RB are interleukin 17 receptor B measurement, cardiovascular disease, body mass index, Abnormality of refraction and hypertension.
How long is the IL17RB protein?
The Homo sapiens IL17RB protein (UniProt Q9NRM6) is 502 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRM6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRM6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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