Olfactomedin-like protein 3 (OLFML3)
Homo sapiens — UniProt Q9NRN5
Data last refreshed: (UniProt release unknown)
Key facts
Olfactomedin-like protein 3 (OLFML3) is a protein from Homo sapiens identified by UniProt accession Q9NRN5, 406 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q9NRN5; gene symbol OLFML3.
- Organism: Homo sapiens.
- Length: 406 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, prostate carcinoma and prostate cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactomedin-like protein 3 |
|---|---|
| UniProt accession | Q9NRN5 |
| Gene | OLFML3 |
| Organism | Homo sapiens |
| Length | 406 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.16
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- Familial prostate cancer · score 0.11
- neoplasm · score 0.09
- hypothyroidism · score 0.08
- colorectal carcinoma · score 0.07
- Red cell distribution width · score 0.06
- glioblastoma multiforme · score 0.05
- colorectal adenocarcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRN5-F1 | alphafold | PREDICTED | 86.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRN5.
Amino-acid sequence (406 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OLFML3?
The strongest Open Targets associations for OLFML3 are heel bone mineral density, prostate carcinoma, prostate cancer, Familial prostate cancer and neoplasm.
How long is the OLFML3 protein?
The Homo sapiens OLFML3 protein (UniProt Q9NRN5) is 406 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRN5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRN5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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