L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (AASDHPPT)
Homo sapiens — UniProt Q9NRN7
Data last refreshed: (UniProt release unknown)
Key facts
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (AASDHPPT) is a protein from Homo sapiens identified by UniProt accession Q9NRN7, 309 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: Q9NRN7; gene symbol AASDHPPT.
- Organism: Homo sapiens.
- Length: 309 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, protein measurement and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
|---|---|
| UniProt accession | Q9NRN7 |
| Gene | AASDHPPT |
| Organism | Homo sapiens |
| Length | 309 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- protein measurement · score 0.22
- mathematical ability · score 0.06
- self reported educational attainment · score 0.05
- age at first sexual intercourse measurement · score 0.05
- cognitive function measurement · score 0.05
- Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
- iridocorneal endothelial syndrome · score 0.04
- X-linked intellectual disability-retinitis pigmentosa syndrome · score 0.04
- Tietz syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRN7-F1 | alphafold | PREDICTED | 90.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRN7.
Amino-acid sequence (309 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AASDHPPT?
The strongest Open Targets associations for AASDHPPT are neurodegenerative disease, protein measurement, mathematical ability, self reported educational attainment and age at first sexual intercourse measurement.
How long is the AASDHPPT protein?
The Homo sapiens AASDHPPT protein (UniProt Q9NRN7) is 309 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRN7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRN7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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