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Serine/threonine-protein kinase 36 (STK36)

Homo sapiens — UniProt Q9NRP7

Gene: STK36Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Serine/threonine-protein kinase 36 (STK36) is a protein from Homo sapiens identified by UniProt accession Q9NRP7, 1315 residues long. MolForge cross-references it against 9 known binders and 331 disease associations.

  • UniProt accession: Q9NRP7; gene symbol STK36.
  • Organism: Homo sapiens.
  • Length: 1315 amino acids.
  • Top disease associations (Open Targets): ciliary dyskinesia, primary, 46, primary ciliary dyskinesia and neurodegenerative disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSerine/threonine-protein kinase 36
UniProt accessionQ9NRP7
GeneSTK36
OrganismHomo sapiens
Length1315 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (331)

Diseases linked to this target (Open Targets).

  • ciliary dyskinesia, primary, 46 · score 0.48
  • primary ciliary dyskinesia · score 0.37
  • neurodegenerative disease · score 0.32
  • diastolic blood pressure · score 0.28
  • erythrocyte count · score 0.26
  • triglyceride measurement · score 0.23
  • body height · score 0.21
  • hemoglobin measurement · score 0.20
  • red blood cell density measurement · score 0.18
  • reticulocyte count · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NRP7-F1alphafoldPREDICTED80.87—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRP7.

Amino-acid sequence (1315 residues)

MEKYHVLEMI GEGSFGRVYK GRRKYSAQVV ALKFIPKLGR SEKELRNLQR EIEIMRGLRH PNIVHMLDSF ETDKEVVVVT DYAEGELFQI LEDDGKLPED QVQAIAAQLV SALYYLHSHR ILHRDMKPQN ILLAKGGGIK LCDFGFARAM STNTMVLTSI KGTPLYMSPE LVEERPYDHT ADLWSVGCIL YELAVGTPPF YATSIFQLVS LILKDPVRWP STISPCFKNF LQGLLTKDPR QRLSWPDLLY HPFIAGHVTI ITEPAGPDLG TPFTSRLPPE LQVLKDEQAH RLAPKGNQSR ILTQAYKRMA EEAMQKKHQN TGPALEQEDK TSKVAPGTAP LPRLGATPQE SSLLAGILAS ELKSSWAKSG TGEVPSAPRE NRTTPDCERA FPEERPEVLG QRSTDVVDLE NEEPDSDNEW QHLLETTEPV PIQLKAPLTL LCNPDFCQRI QSQLHEAGGQ ILKGILEGAS HILPAFRVLS SLLSSCSDSV ALYSFCREAG LPGLLLSLLR HSQESNSLQQ QSWYGTFLQD LMAVIQAYFA CTFNLERSQT SDSLQVFQEA ANLFLDLLGK LLAQPDDSEQ TLRRDSLMCF TVLCEAMDGN SRAISKAFYS SLLTTQQVVL DGLLHGLTVP QLPVHTPQGA PQVSQPLREQ SEDIPGAISS ALAAICTAPV GLPDCWDAKE QVCWHLANQL TEDSSQLRPS LISGLQHPIL CLHLLKVLYS CCLVSEGLCR LLGQEPLALE SLFMLIQGKV KVVDWEESTE VTLYFLSLLV FRLQNLPCGM EKLGSDVATL FTHSHVVSLV SAAACLLGQL GQQGVTFDLQ PMEWMAAATH ALSAPAEVRL TPPGSCGFYD GLLILLLQLL TEQGKASLIR DMSSSEMWTV LWHRFSMVLR LPEEASAQEG ELSLSSPPSP EPDWTLISPQ GMAALLSLAM ATFTQEPQLC LSCLSQHGSI LMSILKHLLC PSFLNQLRQA PHGSEFLPVV VLSVCQLLCF PFALDMDADL LIGVLADLRD SEVAAHLLQV CCYHLPLMQV ELPISLLTRL ALMDPTSLNQ FVNTVSASPR TIVSFLSVAL LSDQPLLTSD LLSLLAHTAR VLSPSHLSFI QELLAGSDES YRPLRSLLGH PENSVRAHTY RLLGHLLQHS MALRGALQSQ SGLLSLLLLG LGDKDPVVRC SASFAVGNAA YQAGPLGPAL AAAVPSMTQL LGDPQAGIRR NVASALGNLG PEGLGEELLQ CEVPQRLLEM ACGDPQPNVK EAALIALRSL QQEPGIHQVL VSLGASEKLS LLSLGNQSLP HSSPRPASAK HCRKLIHLLR PAHSM

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with STK36?

The strongest Open Targets associations for STK36 are ciliary dyskinesia, primary, 46, primary ciliary dyskinesia, neurodegenerative disease, diastolic blood pressure and erythrocyte count.

How long is the STK36 protein?

The Homo sapiens STK36 protein (UniProt Q9NRP7) is 1315 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NRP7
GeneSTK36
OrganismHomo sapiens
Length1315
Binders9
Diseases331
View on UniProt