Phospholipid scramblase 4 (PLSCR4)
Homo sapiens — UniProt Q9NRQ2
Data last refreshed: (UniProt release unknown)
Key facts
Phospholipid scramblase 4 (PLSCR4) is a protein from Homo sapiens identified by UniProt accession Q9NRQ2, 329 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.
- UniProt accession: Q9NRQ2; gene symbol PLSCR4.
- Organism: Homo sapiens.
- Length: 329 amino acids.
- Top disease associations (Open Targets): lymphocyte count, hemoglobin measurement and hematocrit.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Phospholipid scramblase 4 |
|---|---|
| UniProt accession | Q9NRQ2 |
| Gene | PLSCR4 |
| Organism | Homo sapiens |
| Length | 329 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (60)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.43
- hemoglobin measurement · score 0.43
- hematocrit · score 0.39
- red blood cell density measurement · score 0.32
- platelet crit · score 0.31
- bone density · score 0.31
- urate measurement · score 0.31
- sensorineural hearing loss · score 0.12
- Sensorineural hearing impairment · score 0.12
- osteoarthritis · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRQ2-F1 | alphafold | PREDICTED | 69.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRQ2.
Amino-acid sequence (329 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PLSCR4?
The strongest Open Targets associations for PLSCR4 are lymphocyte count, hemoglobin measurement, hematocrit, red blood cell density measurement and platelet crit.
How long is the PLSCR4 protein?
The Homo sapiens PLSCR4 protein (UniProt Q9NRQ2) is 329 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRQ2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRQ2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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