CDC42 small effector protein 1 (CDC42SE1)
Homo sapiens — UniProt Q9NRR8
Data last refreshed: (UniProt release unknown)
Key facts
CDC42 small effector protein 1 (CDC42SE1) is a protein from Homo sapiens identified by UniProt accession Q9NRR8, 79 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q9NRR8; gene symbol CDC42SE1.
- Organism: Homo sapiens.
- Length: 79 amino acids.
- Top disease associations (Open Targets): body mass index, body height and osteoporosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CDC42 small effector protein 1 |
|---|---|
| UniProt accession | Q9NRR8 |
| Gene | CDC42SE1 |
| Organism | Homo sapiens |
| Length | 79 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- body mass index · score 0.26
- body height · score 0.17
- osteoporosis · score 0.13
- generalized anxiety disorder · score 0.09
- age at first sexual intercourse measurement · score 0.09
- waist circumference · score 0.08
- monocyte count · score 0.06
- age at menarche · score 0.06
- non-melanoma skin carcinoma · score 0.05
- skin cancer · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRR8-F1 | alphafold | PREDICTED | 68.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRR8.
Amino-acid sequence (79 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDC42SE1?
The strongest Open Targets associations for CDC42SE1 are body mass index, body height, osteoporosis, generalized anxiety disorder and age at first sexual intercourse measurement.
How long is the CDC42SE1 protein?
The Homo sapiens CDC42SE1 protein (UniProt Q9NRR8) is 79 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRR8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRR8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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