Metal transporter CNNM1 (CNNM1)
Homo sapiens — UniProt Q9NRU3
Data last refreshed: (UniProt release unknown)
Key facts
Metal transporter CNNM1 (CNNM1) is a protein from Homo sapiens identified by UniProt accession Q9NRU3, 951 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q9NRU3; gene symbol CNNM1.
- Organism: Homo sapiens.
- Length: 951 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): aspartate aminotransferase measurement, breast ductal adenocarcinoma and adolescent idiopathic scoliosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Metal transporter CNNM1 |
|---|---|
| UniProt accession | Q9NRU3 |
| Gene | CNNM1 |
| Organism | Homo sapiens |
| Length | 951 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- aspartate aminotransferase measurement · score 0.41
- breast ductal adenocarcinoma · score 0.11
- adolescent idiopathic scoliosis · score 0.10
- metabolite measurement · score 0.06
- childhood onset asthma · score 0.05
- central nervous system cancer · score 0.04
- Red cell distribution width · score 0.03
- mean corpuscular volume · score 0.03
- monocyte percentage of leukocytes · score 0.02
- medulloblastoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRU3-F1 | alphafold | PREDICTED | 66.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRU3.
Amino-acid sequence (951 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CNNM1?
The strongest Open Targets associations for CNNM1 are aspartate aminotransferase measurement, breast ductal adenocarcinoma, adolescent idiopathic scoliosis, metabolite measurement and childhood onset asthma.
How long is the CNNM1 protein?
The Homo sapiens CNNM1 protein (UniProt Q9NRU3) is 951 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRU3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRU3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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