Heme-binding protein 1 (HEBP1)
Homo sapiens — UniProt Q9NRV9
Data last refreshed: (UniProt release unknown)
Key facts
Heme-binding protein 1 (HEBP1) is a protein from Homo sapiens identified by UniProt accession Q9NRV9, 189 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q9NRV9; gene symbol HEBP1.
- Organism: Homo sapiens.
- Length: 189 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, mean corpuscular hemoglobin concentration and mean reticulocyte volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Heme-binding protein 1 |
|---|---|
| UniProt accession | Q9NRV9 |
| Gene | HEBP1 |
| Organism | Homo sapiens |
| Length | 189 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.47
- mean corpuscular hemoglobin concentration · score 0.43
- mean reticulocyte volume · score 0.39
- erythrocyte count · score 0.39
- mean corpuscular hemoglobin · score 0.39
- red blood cell density measurement · score 0.31
- neurodegenerative disease · score 0.21
- serum albumin measurement · score 0.09
- Ehlers-Danlos syndrome · score 0.08
- vital capacity · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRV9-F1 | alphafold | PREDICTED | 84.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRV9.
Amino-acid sequence (189 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HEBP1?
The strongest Open Targets associations for HEBP1 are mean corpuscular volume, mean corpuscular hemoglobin concentration, mean reticulocyte volume, erythrocyte count and mean corpuscular hemoglobin.
How long is the HEBP1 protein?
The Homo sapiens HEBP1 protein (UniProt Q9NRV9) is 189 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRV9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRV9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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