Ras-related protein Rab-6B (RAB6B)
Homo sapiens — UniProt Q9NRW1
Data last refreshed: (UniProt release unknown)
Key facts
Ras-related protein Rab-6B (RAB6B) is a protein from Homo sapiens identified by UniProt accession Q9NRW1, 208 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q9NRW1; gene symbol RAB6B.
- Organism: Homo sapiens.
- Length: 208 amino acids.
- Top disease associations (Open Targets): mean corpuscular hemoglobin concentration, blood protein measurement and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-related protein Rab-6B |
|---|---|
| UniProt accession | Q9NRW1 |
| Gene | RAB6B |
| Organism | Homo sapiens |
| Length | 208 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin concentration · score 0.41
- blood protein measurement · score 0.38
- mean corpuscular hemoglobin · score 0.36
- mean corpuscular volume · score 0.34
- mean reticulocyte volume · score 0.29
- hepatocellular carcinoma · score 0.08
- neoplasm · score 0.06
- alcohol drinking · score 0.05
- colorectal cancer · score 0.04
- colorectal adenoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRW1-F1 | alphafold | PREDICTED | 85.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRW1.
Amino-acid sequence (208 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAB6B?
The strongest Open Targets associations for RAB6B are mean corpuscular hemoglobin concentration, blood protein measurement, mean corpuscular hemoglobin, mean corpuscular volume and mean reticulocyte volume.
How long is the RAB6B protein?
The Homo sapiens RAB6B protein (UniProt Q9NRW1) is 208 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRW1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRW1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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