Large ribosomal subunit protein bL17m (MRPL17)
Homo sapiens — UniProt Q9NRX2
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein bL17m (MRPL17) is a protein from Homo sapiens identified by UniProt accession Q9NRX2, 175 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q9NRX2; gene symbol MRPL17.
- Organism: Homo sapiens.
- Length: 175 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hematocrit and hemoglobin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein bL17m |
|---|---|
| UniProt accession | Q9NRX2 |
| Gene | MRPL17 |
| Organism | Homo sapiens |
| Length | 175 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- hematocrit · score 0.02
- hemoglobin measurement · score 0.02
- cancer · score 0.02
- hypertension · score 0.01
- ovarian carcinoma · score 0.01
- neoplasm · score 0.01
- polycystic ovary syndrome · score 0.01
- glioblastoma multiforme · score 0.00
- Alzheimer disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRX2-F1 | alphafold | PREDICTED | 93.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRX2.
Amino-acid sequence (175 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPL17?
The strongest Open Targets associations for MRPL17 are neurodegenerative disease, hematocrit, hemoglobin measurement, cancer and hypertension.
How long is the MRPL17 protein?
The Homo sapiens MRPL17 protein (UniProt Q9NRX2) is 175 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRX2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRX2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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