Serine incorporator 1 (SERINC1)
Homo sapiens — UniProt Q9NRX5
Data last refreshed: (UniProt release unknown)
Key facts
Serine incorporator 1 (SERINC1) is a protein from Homo sapiens identified by UniProt accession Q9NRX5, 453 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q9NRX5; gene symbol SERINC1.
- Organism: Homo sapiens.
- Length: 453 amino acids.
- Top disease associations (Open Targets): leukocyte count, lymphocyte count and neutrophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine incorporator 1 |
|---|---|
| UniProt accession | Q9NRX5 |
| Gene | SERINC1 |
| Organism | Homo sapiens |
| Length | 453 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.32
- lymphocyte count · score 0.32
- neutrophil count · score 0.30
- mean platelet volume · score 0.29
- erythrocyte count · score 0.23
- monocyte count · score 0.23
- red blood cell density measurement · score 0.22
- mean corpuscular volume · score 0.22
- platelet crit · score 0.22
- platelet count · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRX5-F1 | alphafold | PREDICTED | 77.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRX5.
Amino-acid sequence (453 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SERINC1?
The strongest Open Targets associations for SERINC1 are leukocyte count, lymphocyte count, neutrophil count, mean platelet volume and erythrocyte count.
How long is the SERINC1 protein?
The Homo sapiens SERINC1 protein (UniProt Q9NRX5) is 453 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRX5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRX5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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