Protein kish-B (TMEM167B)
Homo sapiens — UniProt Q9NRX6
Data last refreshed: (UniProt release unknown)
Key facts
Protein kish-B (TMEM167B) is a protein from Homo sapiens identified by UniProt accession Q9NRX6, 74 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q9NRX6; gene symbol TMEM167B.
- Organism: Homo sapiens.
- Length: 74 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, leukocyte count and apolipoprotein B measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein kish-B |
|---|---|
| UniProt accession | Q9NRX6 |
| Gene | TMEM167B |
| Organism | Homo sapiens |
| Length | 74 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.34
- leukocyte count · score 0.23
- apolipoprotein B measurement · score 0.06
- alcohol-related disorders · score 0.06
- bilirubin measurement · score 0.02
- Neurodevelopmental delay · score 0.01
- open-angle glaucoma · score 0.01
- pancreatic carcinoma · score 0.00
- invasive breast ductal carcinoma · score 0.00
- pancreatic ductal adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NRX6-F1 | alphafold | PREDICTED | 70.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NRX6.
Amino-acid sequence (74 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM167B?
The strongest Open Targets associations for TMEM167B are alkaline phosphatase measurement, leukocyte count, apolipoprotein B measurement, alcohol-related disorders and bilirubin measurement.
How long is the TMEM167B protein?
The Homo sapiens TMEM167B protein (UniProt Q9NRX6) is 74 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NRX6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NRX6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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