Gastrokine-1 (GKN1)
Homo sapiens — UniProt Q9NS71
Data last refreshed: (UniProt release unknown)
Key facts
Gastrokine-1 (GKN1) is a protein from Homo sapiens identified by UniProt accession Q9NS71, 185 residues long. MolForge cross-references it against 0 known binders and 84 disease associations.
- UniProt accession: Q9NS71; gene symbol GKN1.
- Organism: Homo sapiens.
- Length: 185 amino acids.
- Top disease associations (Open Targets): muscular dystrophy, gonorrhea and gastric carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Gastrokine-1 |
|---|---|
| UniProt accession | Q9NS71 |
| Gene | GKN1 |
| Organism | Homo sapiens |
| Length | 185 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (84)
Diseases linked to this target (Open Targets).
- muscular dystrophy · score 0.29
- gonorrhea · score 0.08
- gastric carcinoma · score 0.07
- body height · score 0.06
- Obesity · score 0.05
- gut microbiome measurement · score 0.05
- intraocular pressure measurement · score 0.05
- Barrett's esophagus · score 0.05
- gastric non-cardia carcinoma · score 0.04
- primary ovarian insufficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NS71-F1 | alphafold | PREDICTED | 82.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NS71.
Amino-acid sequence (185 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GKN1?
The strongest Open Targets associations for GKN1 are muscular dystrophy, gonorrhea, gastric carcinoma, body height and Obesity.
How long is the GKN1 protein?
The Homo sapiens GKN1 protein (UniProt Q9NS71) is 185 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NS71 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NS71 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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