Ribosome biogenesis protein SLX9 homolog (SLX9)
Homo sapiens — UniProt Q9NSI2
Data last refreshed: (UniProt release unknown)
Key facts
Ribosome biogenesis protein SLX9 homolog (SLX9) is a protein from Homo sapiens identified by UniProt accession Q9NSI2, 230 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q9NSI2; gene symbol SLX9.
- Organism: Homo sapiens.
- Length: 230 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, deafness and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ribosome biogenesis protein SLX9 homolog |
|---|---|
| UniProt accession | Q9NSI2 |
| Gene | SLX9 |
| Organism | Homo sapiens |
| Length | 230 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.16
- deafness · score 0.06
- protein measurement · score 0.05
- benign adult familial myoclonic epilepsy · score 0.04
- blood protein measurement · score 0.03
- PHF-tau measurement · score 0.03
- HbA1c measurement · score 0.03
- lean body mass · score 0.03
- body fat percentage · score 0.02
- age at first birth measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NSI2-F1 | alphafold | PREDICTED | 71.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NSI2.
Amino-acid sequence (230 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLX9?
The strongest Open Targets associations for SLX9 are heel bone mineral density, deafness, protein measurement, benign adult familial myoclonic epilepsy and blood protein measurement.
How long is the SLX9 protein?
The Homo sapiens SLX9 protein (UniProt Q9NSI2) is 230 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NSI2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NSI2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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