Immunoglobulin superfamily member 5 (IGSF5)
Homo sapiens — UniProt Q9NSI5
Data last refreshed: (UniProt release unknown)
Key facts
Immunoglobulin superfamily member 5 (IGSF5) is a protein from Homo sapiens identified by UniProt accession Q9NSI5, 407 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q9NSI5; gene symbol IGSF5.
- Organism: Homo sapiens.
- Length: 407 amino acids.
- Top disease associations (Open Targets): genetic disorder, asthma and drug use measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Immunoglobulin superfamily member 5 |
|---|---|
| UniProt accession | Q9NSI5 |
| Gene | IGSF5 |
| Organism | Homo sapiens |
| Length | 407 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.15
- asthma · score 0.13
- drug use measurement · score 0.11
- metabolite measurement · score 0.05
- head and neck squamous cell carcinoma · score 0.02
- bone density · score 0.02
- urate measurement · score 0.02
- pleurisy · score 0.02
- psoriasis · score 0.02
- astrocytoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NSI5-F1 | alphafold | PREDICTED | 65.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NSI5.
Amino-acid sequence (407 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IGSF5?
The strongest Open Targets associations for IGSF5 are genetic disorder, asthma, drug use measurement, metabolite measurement and head and neck squamous cell carcinoma.
How long is the IGSF5 protein?
The Homo sapiens IGSF5 protein (UniProt Q9NSI5) is 407 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NSI5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NSI5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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