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SAM domain-containing protein SAMSN-1 (SAMSN1)

Homo sapiens — UniProt Q9NSI8

Gene: SAMSN1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

SAM domain-containing protein SAMSN-1 (SAMSN1) is a protein from Homo sapiens identified by UniProt accession Q9NSI8, 373 residues long. MolForge cross-references it against 0 known binders and 201 disease associations.

  • UniProt accession: Q9NSI8; gene symbol SAMSN1.
  • Organism: Homo sapiens.
  • Length: 373 amino acids.
  • Top disease associations (Open Targets): protein measurement, drug use measurement and inflammatory bowel disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSAM domain-containing protein SAMSN-1
UniProt accessionQ9NSI8
GeneSAMSN1
OrganismHomo sapiens
Length373 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (201)

Diseases linked to this target (Open Targets).

  • protein measurement · score 0.27
  • drug use measurement · score 0.22
  • inflammatory bowel disease · score 0.20
  • Miyoshi myopathy · score 0.10
  • neoplasm · score 0.09
  • chronic obstructive pulmonary disease · score 0.08
  • glioblastoma multiforme · score 0.08
  • multiple myeloma · score 0.07
  • acute lung injury · score 0.06
  • common variable immunodeficiency · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NSI8-F1alphafoldPREDICTED63.35—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NSI8.

Amino-acid sequence (373 residues)

MLKRKPSNVS EKEKHQKPKR SSSFGNFDRF RNNSLSKPDD STEAHEGDPT NGSGEQSKTS NNGGGLGKKM RAISWTMKKK VGKKYIKALS EEKDEEDGEN AHPYRNSDPV IGTHTEKVSL KASDSMDSLY SGQSSSSGIT SCSDGTSNRD SFRLDDDGPY SGPFCGRARV HTDFTPSPYD TDSLKIKKGD IIDIICKTPM GMWTGMLNNK VGNFKFIYVD VISEEEAAPK KIKANRRSNS KKSKTLQEFL ERIHLQEYTS TLLLNGYETL EDLKDIKESH LIELNIENPD DRRRLLSAAE NFLEEEIIQE QENEPEPLSL SSDISLNKSQ LDDCPRDSGC YISSGNSDNG KEDLESENLS DMVHKIIITE PSD

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SAMSN1?

The strongest Open Targets associations for SAMSN1 are protein measurement, drug use measurement, inflammatory bowel disease, Miyoshi myopathy and neoplasm.

How long is the SAMSN1 protein?

The Homo sapiens SAMSN1 protein (UniProt Q9NSI8) is 373 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NSI8
GeneSAMSN1
OrganismHomo sapiens
Length373
Binders0
Diseases201
View on UniProt