Kinesin light chain 4 (KLC4)
Homo sapiens — UniProt Q9NSK0
Data last refreshed: (UniProt release unknown)
Key facts
Kinesin light chain 4 (KLC4) is a protein from Homo sapiens identified by UniProt accession Q9NSK0, 619 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9NSK0; gene symbol KLC4.
- Organism: Homo sapiens.
- Length: 619 amino acids.
- Top disease associations (Open Targets): hemoglobin measurement, low grade glioma and ovarian cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kinesin light chain 4 |
|---|---|
| UniProt accession | Q9NSK0 |
| Gene | KLC4 |
| Organism | Homo sapiens |
| Length | 619 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.21
- low grade glioma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- esophageal cancer · score 0.15
- mean corpuscular hemoglobin concentration · score 0.06
- neoplasm · score 0.05
- vital capacity · score 0.05
- body height · score 0.04
- hereditary spastic paraplegia · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NSK0-F1 | alphafold | PREDICTED | 71.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NSK0.
Amino-acid sequence (619 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KLC4?
The strongest Open Targets associations for KLC4 are hemoglobin measurement, low grade glioma, ovarian cancer, breast adenocarcinoma and esophageal cancer.
How long is the KLC4 protein?
The Homo sapiens KLC4 protein (UniProt Q9NSK0) is 619 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NSK0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NSK0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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