Protein FAM217B (FAM217B)

About Protein FAM217B

Protein FAM217B (FAM217B) is a protein from Homo sapiens identified by UniProt accession Q9NTX9, 383 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Protein FAM217B
UniProt accession	Q9NTX9
Gene	FAM217B
Organism	Homo sapiens
Length	383 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (40)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.28
mathematical ability · score 0.13
metabolite measurement · score 0.13
self reported educational attainment · score 0.13
reticulocyte count · score 0.12
breast milk measurement · score 0.11
brachial plexus neuropathy · score 0.09
adolescent idiopathic scoliosis · score 0.09
rheumatoid arthritis · score 0.09
lymphocyte count · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NTX9-F1	alphafold	PREDICTED	57.18	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NTX9.

Amino-acid sequence (383 residues)

MNAGPSWNKV QHSKNSSGKR QSKSQVPHAS SQPRSSLTAV TQPTEEKLKE SISPEARRKR NPLGSRCQGA SGNKLFLDFQ SMKIIKENAD EDSASDLSDS ERIPIPPSPL TPPDLNLRAE EIDPVYFDLH PGQGHTKPEY YYPNFLPSPF SSWDLRDMAL LLNAENKTEA VPRVGGLLGK YIDRLIQLEW LQVQTVQCEK AKGGKARPPT APGTSGALKS PGRSKLIASA LSKPLPHQEG ASKSGPSRKK AFHHEEIHPS HYAFETSPRP IDVLGGTRFC SQRQTLEMRT EEKKKKSSKS TKLQRWDLSG SGSSSKVETS GHIRVPKQAA VILDSADSCK ASKTQAHAHP RKKGKAESCG HATVSSEKKL KTNGVKQNTY KLK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards