RNA-binding protein 12 (RBM12)
Homo sapiens — UniProt Q9NTZ6
Data last refreshed: (UniProt release unknown)
Key facts
RNA-binding protein 12 (RBM12) is a protein from Homo sapiens identified by UniProt accession Q9NTZ6, 932 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q9NTZ6; gene symbol RBM12.
- Organism: Homo sapiens.
- Length: 932 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, schizophrenia and sitting height measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RNA-binding protein 12 |
|---|---|
| UniProt accession | Q9NTZ6 |
| Gene | RBM12 |
| Organism | Homo sapiens |
| Length | 932 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- schizophrenia · score 0.42
- sitting height measurement · score 0.23
- lysosomal storage disease · score 0.22
- mean platelet volume · score 0.14
- BMI-adjusted waist circumference · score 0.12
- Neurodevelopmental delay · score 0.12
- body height · score 0.11
- cognitive function measurement · score 0.11
- intelligence · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NTZ6-F1 | alphafold | PREDICTED | 64.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NTZ6.
Amino-acid sequence (932 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RBM12?
The strongest Open Targets associations for RBM12 are neurodegenerative disease, schizophrenia, sitting height measurement, lysosomal storage disease and mean platelet volume.
How long is the RBM12 protein?
The Homo sapiens RBM12 protein (UniProt Q9NTZ6) is 932 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NTZ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NTZ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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