Ankyrin repeat and EF-hand domain-containing protein 1 (ANKEF1)
Homo sapiens — UniProt Q9NU02
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat and EF-hand domain-containing protein 1 (ANKEF1) is a protein from Homo sapiens identified by UniProt accession Q9NU02, 776 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q9NU02; gene symbol ANKEF1.
- Organism: Homo sapiens.
- Length: 776 amino acids.
- Top disease associations (Open Targets): nose morphology measurement, neuroimaging measurement and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat and EF-hand domain-containing protein 1 |
|---|---|
| UniProt accession | Q9NU02 |
| Gene | ANKEF1 |
| Organism | Homo sapiens |
| Length | 776 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- nose morphology measurement · score 0.33
- neuroimaging measurement · score 0.27
- reticulocyte count · score 0.08
- aortic measurement · score 0.03
- reticulocyte measurement · score 0.03
- heel bone mineral density · score 0.02
- diastolic blood pressure · score 0.02
- cancer · score 0.01
- Abnormal sperm morphology · score 0.01
- Sepsis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NU02-F1 | alphafold | PREDICTED | 80.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NU02.
Amino-acid sequence (776 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKEF1?
The strongest Open Targets associations for ANKEF1 are nose morphology measurement, neuroimaging measurement, reticulocyte count, aortic measurement and reticulocyte measurement.
How long is the ANKEF1 protein?
The Homo sapiens ANKEF1 protein (UniProt Q9NU02) is 776 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NU02 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NU02 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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