TBC1 domain family member 22B (TBC1D22B)
Homo sapiens — UniProt Q9NU19
Data last refreshed: (UniProt release unknown)
Key facts
TBC1 domain family member 22B (TBC1D22B) is a protein from Homo sapiens identified by UniProt accession Q9NU19, 505 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q9NU19; gene symbol TBC1D22B.
- Organism: Homo sapiens.
- Length: 505 amino acids.
- Top disease associations (Open Targets): platelet count, platelet crit and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TBC1 domain family member 22B |
|---|---|
| UniProt accession | Q9NU19 |
| Gene | TBC1D22B |
| Organism | Homo sapiens |
| Length | 505 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- platelet count · score 0.16
- platelet crit · score 0.13
- mean corpuscular volume · score 0.02
- neutrophil count · score 0.02
- neoplasm · score 0.01
- cryopyrin-associated periodic syndrome · score 0.00
- cutaneous melanoma · score 0.00
- visceral Leishmaniasis · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NU19-F1 | alphafold | PREDICTED | 75.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NU19.
Amino-acid sequence (505 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TBC1D22B?
The strongest Open Targets associations for TBC1D22B are platelet count, platelet crit, mean corpuscular volume, neutrophil count and neoplasm.
How long is the TBC1D22B protein?
The Homo sapiens TBC1D22B protein (UniProt Q9NU19) is 505 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NU19 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NU19 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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