LYR motif-containing protein 2 (LYRM2)
Homo sapiens — UniProt Q9NU23
Data last refreshed: (UniProt release unknown)
Key facts
LYR motif-containing protein 2 (LYRM2) is a protein from Homo sapiens identified by UniProt accession Q9NU23, 88 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q9NU23; gene symbol LYRM2.
- Organism: Homo sapiens.
- Length: 88 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lean body mass and fat body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | LYR motif-containing protein 2 |
|---|---|
| UniProt accession | Q9NU23 |
| Gene | LYRM2 |
| Organism | Homo sapiens |
| Length | 88 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.34
- lean body mass · score 0.33
- fat body mass · score 0.29
- whole body water mass · score 0.25
- body mass index · score 0.25
- Red cell distribution width · score 0.23
- coronary artery disease · score 0.19
- base metabolic rate measurement · score 0.16
- body weight · score 0.11
- pulse pressure measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NU23-F1 | alphafold | PREDICTED | 92.49 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NU23.
Amino-acid sequence (88 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LYRM2?
The strongest Open Targets associations for LYRM2 are neurodegenerative disease, lean body mass, fat body mass, whole body water mass and body mass index.
How long is the LYRM2 protein?
The Homo sapiens LYRM2 protein (UniProt Q9NU23) is 88 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NU23 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NU23 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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