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Forkhead box protein D4-like 1 (FOXD4L1)

Homo sapiens — UniProt Q9NU39

Gene: FOXD4L1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Forkhead box protein D4-like 1 (FOXD4L1) is a protein from Homo sapiens identified by UniProt accession Q9NU39, 408 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

  • UniProt accession: Q9NU39; gene symbol FOXD4L1.
  • Organism: Homo sapiens.
  • Length: 408 amino acids.
  • Top disease associations (Open Targets): functional brain measurement, blood protein measurement and language measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameForkhead box protein D4-like 1
UniProt accessionQ9NU39
GeneFOXD4L1
OrganismHomo sapiens
Length408 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (17)

Diseases linked to this target (Open Targets).

  • functional brain measurement · score 0.08
  • blood protein measurement · score 0.08
  • language measurement · score 0.06
  • Isolated anophthalmia - microphthalmia · score 0.05
  • Microphthalmia - ankyloblepharon - intellectual disability · score 0.05
  • sleep duration · score 0.05
  • nanophthalmia · score 0.04
  • nanophthalmos 2 · score 0.04
  • microphthalmia · score 0.04
  • insomnia measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NU39-F1alphafoldPREDICTED58.15—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NU39.

Amino-acid sequence (408 residues)

MNLPRAERPR STPQRSLRDS DGEDGKIDVL GEEEDEDEVE DEEEEASQKF LEQSLQPGLQ VARWGGVALP REHIEGGGPS DPSEFGTEFR APPRSAAASE DARQPAKPPY SYIALITMAI LQSPHKRLTL SGICAFISGR FPYYRRKFPA WQNSIRHNLS LNDCFVKIPR EPGHPGKGTY WSLDPASQDM FDNGSFLRRR KRFKRHQLTP GAHLPHPFPL PAAHAALHNP RPGPLLGAPA LPQPVPGAYP NTAPGRRPYA LLHPHPPRYL LLSAPAYAGA PKKAEGADLA TPGTLPVLQP SLGPQPWEEG KGLASPPGGG CISFSIESIM QGVRGAGTGA AQSLSPTAWS YCPLLQRPSS LSDNFAATAA ASGGGLRQRL RSHQGRGAGR APVGRVGAAA VSGGGRGL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FOXD4L1?

The strongest Open Targets associations for FOXD4L1 are functional brain measurement, blood protein measurement, language measurement, Isolated anophthalmia - microphthalmia and Microphthalmia - ankyloblepharon - intellectual disability.

How long is the FOXD4L1 protein?

The Homo sapiens FOXD4L1 protein (UniProt Q9NU39) is 408 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NU39
GeneFOXD4L1
OrganismHomo sapiens
Length408
Binders0
Diseases17
View on UniProt