Glycoprotein integral membrane protein 1 (GINM1)
Homo sapiens — UniProt Q9NU53
Data last refreshed: (UniProt release unknown)
Key facts
Glycoprotein integral membrane protein 1 (GINM1) is a protein from Homo sapiens identified by UniProt accession Q9NU53, 330 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: Q9NU53; gene symbol GINM1.
- Organism: Homo sapiens.
- Length: 330 amino acids.
- Top disease associations (Open Targets): refractive error measurement, cortical thickness and brain volume measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glycoprotein integral membrane protein 1 |
|---|---|
| UniProt accession | Q9NU53 |
| Gene | GINM1 |
| Organism | Homo sapiens |
| Length | 330 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- refractive error measurement · score 0.12
- cortical thickness · score 0.09
- brain volume measurement · score 0.09
- brain stem volume measurement · score 0.08
- retinitis pigmentosa · score 0.08
- serum metabolite measurement · score 0.07
- X-linked retinal dysplasia · score 0.07
- Leber congenital amaurosis · score 0.07
- age-related macular degeneration · score 0.06
- Familial exudative vitreoretinopathy · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NU53-F1 | alphafold | PREDICTED | 70.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NU53.
Amino-acid sequence (330 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GINM1?
The strongest Open Targets associations for GINM1 are refractive error measurement, cortical thickness, brain volume measurement, brain stem volume measurement and retinitis pigmentosa.
How long is the GINM1 protein?
The Homo sapiens GINM1 protein (UniProt Q9NU53) is 330 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NU53 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NU53 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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