Zinc finger protein 57 homolog (ZFP57)
Homo sapiens — UniProt Q9NU63
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 57 homolog (ZFP57) is a protein from Homo sapiens identified by UniProt accession Q9NU63, 452 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.
- UniProt accession: Q9NU63; gene symbol ZFP57.
- Organism: Homo sapiens.
- Length: 452 amino acids.
- Top disease associations (Open Targets): transient neonatal diabetes mellitus, transient neonatal diabetes, dominant/recessive and schizophrenia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 57 homolog |
|---|---|
| UniProt accession | Q9NU63 |
| Gene | ZFP57 |
| Organism | Homo sapiens |
| Length | 452 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (80)
Diseases linked to this target (Open Targets).
- transient neonatal diabetes mellitus · score 0.74
- transient neonatal diabetes, dominant/recessive · score 0.46
- schizophrenia · score 0.26
- neurodegenerative disease · score 0.24
- lung carcinoma · score 0.20
- genetic disorder · score 0.19
- albumin:globulin ratio measurement · score 0.17
- monogenic diabetes · score 0.17
- nasopharyngeal neoplasm · score 0.17
- cognitive function measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NU63-F1 | alphafold | PREDICTED | 56.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NU63.
Amino-acid sequence (452 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZFP57?
The strongest Open Targets associations for ZFP57 are transient neonatal diabetes mellitus, transient neonatal diabetes, dominant/recessive, schizophrenia, neurodegenerative disease and lung carcinoma.
How long is the ZFP57 protein?
The Homo sapiens ZFP57 protein (UniProt Q9NU63) is 452 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NU63 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NU63 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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