Zinc finger and BTB domain-containing protein 40 (ZBTB40)
Homo sapiens — UniProt Q9NUA8
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger and BTB domain-containing protein 40 (ZBTB40) is a protein from Homo sapiens identified by UniProt accession Q9NUA8, 1239 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.
- UniProt accession: Q9NUA8; gene symbol ZBTB40.
- Organism: Homo sapiens.
- Length: 1239 amino acids.
- Top disease associations (Open Targets): bone density, heel bone mineral density and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 40 |
|---|---|
| UniProt accession | Q9NUA8 |
| Gene | ZBTB40 |
| Organism | Homo sapiens |
| Length | 1239 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (76)
Diseases linked to this target (Open Targets).
- bone density · score 0.42
- heel bone mineral density · score 0.42
- reticulocyte count · score 0.40
- Red cell distribution width · score 0.40
- bone quantitative ultrasound measurement · score 0.39
- vital capacity · score 0.38
- inflammatory bowel disease · score 0.38
- eosinophil count · score 0.38
- hemoglobin measurement · score 0.38
- hematocrit · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUA8-F1 | alphafold | PREDICTED | 65.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUA8.
Amino-acid sequence (1239 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZBTB40?
The strongest Open Targets associations for ZBTB40 are bone density, heel bone mineral density, reticulocyte count, Red cell distribution width and bone quantitative ultrasound measurement.
How long is the ZBTB40 protein?
The Homo sapiens ZBTB40 protein (UniProt Q9NUA8) is 1239 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUA8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUA8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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