SERTA domain-containing protein 4 (SERTAD4)
Homo sapiens — UniProt Q9NUC0
Data last refreshed: (UniProt release unknown)
Key facts
SERTA domain-containing protein 4 (SERTAD4) is a protein from Homo sapiens identified by UniProt accession Q9NUC0, 356 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q9NUC0; gene symbol SERTAD4.
- Organism: Homo sapiens.
- Length: 356 amino acids.
- Top disease associations (Open Targets): body height, urate measurement and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SERTA domain-containing protein 4 |
|---|---|
| UniProt accession | Q9NUC0 |
| Gene | SERTAD4 |
| Organism | Homo sapiens |
| Length | 356 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- body height · score 0.35
- urate measurement · score 0.29
- systolic blood pressure · score 0.28
- heel bone mineral density · score 0.18
- bone quantitative ultrasound measurement · score 0.15
- smoking initiation · score 0.14
- age at first birth measurement · score 0.12
- smoking behavior · score 0.11
- Abnormality of refraction · score 0.10
- coronary artery disease · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUC0-F1 | alphafold | PREDICTED | 51.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUC0.
Amino-acid sequence (356 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SERTAD4?
The strongest Open Targets associations for SERTAD4 are body height, urate measurement, systolic blood pressure, heel bone mineral density and bone quantitative ultrasound measurement.
How long is the SERTAD4 protein?
The Homo sapiens SERTAD4 protein (UniProt Q9NUC0) is 356 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUC0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUC0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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