Palmitoyltransferase ZDHHC18 (ZDHHC18)
Homo sapiens — UniProt Q9NUE0
Data last refreshed: (UniProt release unknown)
Key facts
Palmitoyltransferase ZDHHC18 (ZDHHC18) is a protein from Homo sapiens identified by UniProt accession Q9NUE0, 388 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: Q9NUE0; gene symbol ZDHHC18.
- Organism: Homo sapiens.
- Length: 388 amino acids.
- Top disease associations (Open Targets): monocyte count, monocyte percentage of leukocytes and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Palmitoyltransferase ZDHHC18 |
|---|---|
| UniProt accession | Q9NUE0 |
| Gene | ZDHHC18 |
| Organism | Homo sapiens |
| Length | 388 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.27
- monocyte percentage of leukocytes · score 0.27
- sex hormone-binding globulin measurement · score 0.26
- neutrophil count · score 0.25
- leukocyte count · score 0.25
- serum gamma-glutamyl transferase measurement · score 0.21
- myeloid white cell count · score 0.21
- heel bone mineral density · score 0.20
- neutrophil percentage of leukocytes · score 0.19
- cardiovascular disease · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUE0-F1 | alphafold | PREDICTED | 79.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUE0.
Amino-acid sequence (388 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZDHHC18?
The strongest Open Targets associations for ZDHHC18 are monocyte count, monocyte percentage of leukocytes, sex hormone-binding globulin measurement, neutrophil count and leukocyte count.
How long is the ZDHHC18 protein?
The Homo sapiens ZDHHC18 protein (UniProt Q9NUE0) is 388 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUE0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUE0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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