Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10)
Homo sapiens — UniProt Q9NUJ1
Data last refreshed: (UniProt release unknown)
Key facts
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) is a protein from Homo sapiens identified by UniProt accession Q9NUJ1, 306 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.
- UniProt accession: Q9NUJ1; gene symbol ABHD10.
- Organism: Homo sapiens.
- Length: 306 amino acids.
- Top disease associations (Open Targets): cutaneous melanoma, lung adenocarcinoma and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Palmitoyl-protein thioesterase ABHD10, mitochondrial |
|---|---|
| UniProt accession | Q9NUJ1 |
| Gene | ABHD10 |
| Organism | Homo sapiens |
| Length | 306 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (85)
Diseases linked to this target (Open Targets).
- cutaneous melanoma · score 0.18
- lung adenocarcinoma · score 0.17
- glioblastoma multiforme · score 0.17
- atrial fibrillation · score 0.11
- squamous cell lung carcinoma · score 0.10
- PR interval · score 0.09
- peak expiratory flow · score 0.08
- FEV/FVC ratio · score 0.07
- lobe attachment · score 0.07
- azoospermia · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUJ1-F1 | alphafold | PREDICTED | 86.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUJ1.
Amino-acid sequence (306 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ABHD10?
The strongest Open Targets associations for ABHD10 are cutaneous melanoma, lung adenocarcinoma, glioblastoma multiforme, atrial fibrillation and squamous cell lung carcinoma.
How long is the ABHD10 protein?
The Homo sapiens ABHD10 protein (UniProt Q9NUJ1) is 306 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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