T-complex protein 11-like protein 1 (TCP11L1)
Homo sapiens — UniProt Q9NUJ3
Data last refreshed: (UniProt release unknown)
Key facts
T-complex protein 11-like protein 1 (TCP11L1) is a protein from Homo sapiens identified by UniProt accession Q9NUJ3, 509 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q9NUJ3; gene symbol TCP11L1.
- Organism: Homo sapiens.
- Length: 509 amino acids.
- Top disease associations (Open Targets): forced expiratory volume, platelet component distribution width and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | T-complex protein 11-like protein 1 |
|---|---|
| UniProt accession | Q9NUJ3 |
| Gene | TCP11L1 |
| Organism | Homo sapiens |
| Length | 509 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- forced expiratory volume · score 0.29
- platelet component distribution width · score 0.29
- neurodegenerative disease · score 0.23
- cystatin C measurement · score 0.23
- vital capacity · score 0.21
- exstrophy-epispadias complex · score 0.12
- heel bone mineral density · score 0.06
- alcohol consumption measurement · score 0.05
- alcohol use disorder measurement · score 0.04
- sleep measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUJ3-F1 | alphafold | PREDICTED | 81.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUJ3.
Amino-acid sequence (509 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TCP11L1?
The strongest Open Targets associations for TCP11L1 are forced expiratory volume, platelet component distribution width, neurodegenerative disease, cystatin C measurement and vital capacity.
How long is the TCP11L1 protein?
The Homo sapiens TCP11L1 protein (UniProt Q9NUJ3) is 509 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUJ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUJ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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