PI-PLC X domain-containing protein 1 (PLCXD1)
Homo sapiens — UniProt Q9NUJ7
Data last refreshed: (UniProt release unknown)
Key facts
PI-PLC X domain-containing protein 1 (PLCXD1) is a protein from Homo sapiens identified by UniProt accession Q9NUJ7, 323 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q9NUJ7; gene symbol PLCXD1.
- Organism: Homo sapiens.
- Length: 323 amino acids.
- Top disease associations (Open Targets): esophageal squamous cell carcinoma, psoriasis and colorectal cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PI-PLC X domain-containing protein 1 |
|---|---|
| UniProt accession | Q9NUJ7 |
| Gene | PLCXD1 |
| Organism | Homo sapiens |
| Length | 323 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- esophageal squamous cell carcinoma · score 0.02
- psoriasis · score 0.01
- colorectal cancer · score 0.01
- Colon Sessile Serrated Adenoma/Polyp · score 0.01
- melanoma · score 0.01
- systemic juvenile idiopathic arthritis · score 0.01
- uterine leiomyosarcoma · score 0.01
- metastatic melanoma · score 0.00
- sessile serrated polyp · score 0.00
- Leri-Weill dyschondrosteosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUJ7-F1 | alphafold | PREDICTED | 93.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUJ7.
Amino-acid sequence (323 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PLCXD1?
The strongest Open Targets associations for PLCXD1 are esophageal squamous cell carcinoma, psoriasis, colorectal cancer, Colon Sessile Serrated Adenoma/Polyp and melanoma.
How long is the PLCXD1 protein?
The Homo sapiens PLCXD1 protein (UniProt Q9NUJ7) is 323 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUJ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUJ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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