Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)
Homo sapiens — UniProt Q9NUL3
Data last refreshed: (UniProt release unknown)
Key facts
Double-stranded RNA-binding protein Staufen homolog 2 (STAU2) is a protein from Homo sapiens identified by UniProt accession Q9NUL3, 570 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.
- UniProt accession: Q9NUL3; gene symbol STAU2.
- Organism: Homo sapiens.
- Length: 570 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist circumference, appendicular lean mass and cortical thickness.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Double-stranded RNA-binding protein Staufen homolog 2 |
|---|---|
| UniProt accession | Q9NUL3 |
| Gene | STAU2 |
| Organism | Homo sapiens |
| Length | 570 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (71)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist circumference · score 0.29
- appendicular lean mass · score 0.27
- cortical thickness · score 0.25
- Inguinal hernia · score 0.24
- peak expiratory flow · score 0.22
- grip strength measurement · score 0.22
- type 2 diabetes mellitus · score 0.22
- body mass index · score 0.18
- cortical surface area measurement · score 0.17
- monocyte count · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUL3-F1 | alphafold | PREDICTED | 70.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUL3.
Amino-acid sequence (570 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STAU2?
The strongest Open Targets associations for STAU2 are BMI-adjusted waist circumference, appendicular lean mass, cortical thickness, Inguinal hernia and peak expiratory flow.
How long is the STAU2 protein?
The Homo sapiens STAU2 protein (UniProt Q9NUL3) is 570 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUL3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUL3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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