Probable ATP-dependent RNA helicase DDX28 (DDX28)
Homo sapiens — UniProt Q9NUL7
Data last refreshed: (UniProt release unknown)
Key facts
Probable ATP-dependent RNA helicase DDX28 (DDX28) is a protein from Homo sapiens identified by UniProt accession Q9NUL7, 540 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q9NUL7; gene symbol DDX28.
- Organism: Homo sapiens.
- Length: 540 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, high density lipoprotein cholesterol measurement and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable ATP-dependent RNA helicase DDX28 |
|---|---|
| UniProt accession | Q9NUL7 |
| Gene | DDX28 |
| Organism | Homo sapiens |
| Length | 540 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.21
- high density lipoprotein cholesterol measurement · score 0.07
- urate measurement · score 0.04
- alcohol consumption measurement · score 0.03
- atopic asthma · score 0.03
- primary biliary cirrhosis · score 0.03
- alcohol drinking · score 0.02
- hemoglobin measurement · score 0.02
- total cholesterol measurement · score 0.02
- chronotype measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUL7-F1 | alphafold | PREDICTED | 83.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUL7.
Amino-acid sequence (540 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DDX28?
The strongest Open Targets associations for DDX28 are alkaline phosphatase measurement, high density lipoprotein cholesterol measurement, urate measurement, alcohol consumption measurement and atopic asthma.
How long is the DDX28 protein?
The Homo sapiens DDX28 protein (UniProt Q9NUL7) is 540 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUL7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUL7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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