tRNA:m(4)X modification enzyme TRM13 homolog (TRMT13)
Homo sapiens — UniProt Q9NUP7
Data last refreshed: (UniProt release unknown)
Key facts
tRNA:m(4)X modification enzyme TRM13 homolog (TRMT13) is a protein from Homo sapiens identified by UniProt accession Q9NUP7, 481 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q9NUP7; gene symbol TRMT13.
- Organism: Homo sapiens.
- Length: 481 amino acids.
- Top disease associations (Open Targets): gut microbiome measurement, Visual loss and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | tRNA:m(4)X modification enzyme TRM13 homolog |
|---|---|
| UniProt accession | Q9NUP7 |
| Gene | TRMT13 |
| Organism | Homo sapiens |
| Length | 481 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- gut microbiome measurement · score 0.04
- Visual loss · score 0.03
- body height · score 0.03
- papillary thyroid carcinoma · score 0.02
- colorectal cancer · score 0.01
- Sepsis · score 0.01
- Pick disease · score 0.01
- juvenile dermatomyositis · score 0.01
- primitive neuroectodermal tumor · score 0.01
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUP7-F1 | alphafold | PREDICTED | 79.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUP7.
Amino-acid sequence (481 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRMT13?
The strongest Open Targets associations for TRMT13 are gut microbiome measurement, Visual loss, body height, papillary thyroid carcinoma and colorectal cancer.
How long is the TRMT13 protein?
The Homo sapiens TRMT13 protein (UniProt Q9NUP7) is 481 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUP7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUP7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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