SPATS2-like protein (SPATS2L)
Homo sapiens — UniProt Q9NUQ6
Data last refreshed: (UniProt release unknown)
Key facts
SPATS2-like protein (SPATS2L) is a protein from Homo sapiens identified by UniProt accession Q9NUQ6, 558 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: Q9NUQ6; gene symbol SPATS2L.
- Organism: Homo sapiens.
- Length: 558 amino acids.
- Top disease associations (Open Targets): schizophrenia, electrocardiography and atrial fibrillation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SPATS2-like protein |
|---|---|
| UniProt accession | Q9NUQ6 |
| Gene | SPATS2L |
| Organism | Homo sapiens |
| Length | 558 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.48
- electrocardiography · score 0.46
- atrial fibrillation · score 0.43
- systolic blood pressure · score 0.41
- FEV/FVC ratio · score 0.41
- reaction time measurement · score 0.39
- appendicular lean mass · score 0.38
- age at first sexual intercourse measurement · score 0.36
- bipolar disorder · score 0.35
- tuberculosis · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUQ6-F1 | alphafold | PREDICTED | 63.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUQ6.
Amino-acid sequence (558 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPATS2L?
The strongest Open Targets associations for SPATS2L are schizophrenia, electrocardiography, atrial fibrillation, systolic blood pressure and FEV/FVC ratio.
How long is the SPATS2L protein?
The Homo sapiens SPATS2L protein (UniProt Q9NUQ6) is 558 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUQ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUQ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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